What is Actemra®?

Actemra® is a brand-name prescription drug. It’s FDA-approved to treat the following conditions:

  • Moderate to severe rheumatoid arthritis (RA) in adults who didn’t have enough improvement in their RA with certain other past treatments.
  • Giant cell arteritis (GCA) in adults.
  • Polyarticular juvenile idiopathic arthritis (PJIA) in children ages 2 years and older.
  • Systemic juvenile idiopathic arthritis (SJIA) in children ages 2 years and older.
  • A type of cytokine release syndrome (CRS) that’s severe or life-threatening after treatment with chimeric antigen receptor (car) t-cell therapy in adults and children ages 2 years and older.

What is the Work Function of Actemra®?

Actemra® is a medicine that affects your immune system. Actemra® can lower the Ability of Your Immune System to fight infections. Some people have serious infections while taking Actemra®, including tuberculosis (TB), and infections caused by bacteria, fungi, or viruses that can spread throughout the body. Some people have died from these infections. Your healthcare provider should test you for TB before starting Actemra®.

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Side Effects of Actemra®:

Side Effects of Actemra® includes:

  • Hepatitis B infection.
  • Feel Very Tired.
  • Vomiting.
  • Chills.
  • Dark Urine.
  • Skin or Eyes Look Yellow.
  • Clay-colored Bowel Movements.
  • Stomach Discomfort.
  • Skin Rash.
  • Little or No Appetite.
  • Fevers.
  • Muscle Aches.
  • Serious Allergic Reactions.
  • Shortness of Breath or Trouble Breathing.
  • Swelling of The Lips, Tongue, or Face.
  • Chest Pain.
  • Feeling Dizzy or Faint.
  • Moderate or Severe Abdominal Pain or Vomiting.
  • Nervous System Problem.
The Most Common Side Effects of Actemra® include:
  • Upper Respiratory Tract infections (Common Cold, Sinus infections).
  • Headache.
  • increased Blood Pressure (Hypertension).
  • injection Site Reactions.

Cautions To Take Actemra®:

There are some Cautions To Take Actemra®. But Actemra® affects the immune system. You may get infections more easily, even serious or fatal infections. Consult your doctors immediately if you have:

  • Fever.
  • Chills.
  • Aches.
  • Tiredness.
  • Cough.
  • Skin.
  • Sores.
  • Diarrhea.
  • Weight Loss.
  • Burning With Urinate. 
  • Stomach Pain.
  • Vomiting.
  • Loss of Appetite.
  • Tiredness.
  • Dark Urine.
  • Clay Colored Stools.
  • Pale Complexion.
  • Yellow Eyes.
  • Breast Feeding.
  • Pregnancy.

Frequently Asked Question

1. What should I avoid while receiving Actemra®?

Do not receive a "live" vaccine or you could develop a serious infection. The vaccine may not work as well and may not fully protect you from disease. Ask your doctor before getting any vaccine.

2. What other drugs may affect Actemra®?

Sometimes it is not safe to use certain medications at the same time. Tell your doctor about all your other medicines, especially other medicines to treat rheumatoid arthritis, such as:

  • abatacept, etanercept;
  • anakinra; or
  • adalimumab, certolizumab, golimumab, infliximab, or rituximab.
3. How does Actemra® work?

Biologic drugs are synthetically engineering to be related to a protein that occurs naturally in the body. They are used to suppress the immune system in autoimmune disease.

4. What is the recommended dosage of Actemra®?

The recommended dosage of Actemra® for adult patients given as a 60-minute single intravenous (IV) drip infusion is 4 mg/kg every 4 weeks followed by an increase to 8 mg/kg every 4 weeks based on clinical response.