What is Opdivo® ?

Opdivo® is a medicine that may Treat Certain Cancers by working with your immune system.  Opdivo®  can cause your immune system to attack normal organs and tissues in any area of your body and can affect the way they work. Some of these problems may happen more often when Opdivo®  is used in combination with another therapy.

How Does Opdivo® Work?

Opdivo® has been designed to attach to a receptor called PD-1, found on certain cells of the immune system called T cells. Cancer Cells can produce proteins (PD-L1 and PD-L2) that attach to this receptor, switching off the T cells. By attaching to the receptor, nivolumab prevents cancer cells from switching off T cells, thereby increasing the ability of the immune system to kill cancer cells.

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How Do I Take Opdivo®?

The recommended therapy varies for the different indications and depends on whether nivolumab is used alone or in combination with other therapeutics. Complete information about Nivolumab Dosage and administration for some of the countries of approval can be found in the official prescribing information listed in our references section which can be ordered.

What Are Uses of Opdivo®? 

Opdivo® is used to treat cancer. So if you have Cancer Symptoms you can get this. It works by changing the action of your own immune system, directing it to attack cancer cells. Nivolumab belongs to a class of drugs known as monoclonal antibodies.

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Side Effects of Opdivo®:

Common side effects include but are not limited to:

  • Fatigue
  • Lymphocytopenia (Low White Blood Cells)
  • Low Sodium
  • Shortness of Breath
  • Musculoskeletal Pain
  • Decreased Appetite
  • Cough
  • Nausea
  • Anemia
  • Constipation
  • Increased Serum Creatinine
  • Colitis
  • Low Potassium
  • Low Magnesium
  • High Calcium
  • Vomiting
  • Weakness
  • Diarrhea
  • High Potassium
  • Low Calcium
  • Swelling
  • Fever
  • Rash
  • Abdominal Pain
  • Increased Serum AST
  • Thrombocytopenia
  • Increased Serum Alkaline Phosphatase
  • Chest Pain
  • Weight Loss
  • Joint Pain
  • Increased Serum ALT
  • Itching
  • Pneumonia
  • Pain

Cautions To Take Opdivo®:

  1. Before starting Opdivo®, tell your doctor about any other medications you are taking.
  2. Do not receive any kind of immunization or vaccination without your doctor's approval while taking Opdivo®
  3. Inform your health care professional if you are pregnant or may be pregnant prior to starting this treatment.
  4. For both men and women: Do not conceive a child (get pregnant) while taking Opdivo®.
  5. Do not breastfeed while taking this medication.

Frequently Asked Questions

1. How Opdivo® is given?

Opdivo® will be given to you in a hospital or clinic under the supervision of an experienced doctor. It will be given to you as an infusion (a drip) into a vein (intravenously). Your doctor will decide how many treatments you need.

2. What happens if I miss a dose?

It is very important for you to keep all appointments to receiving Opdivo®. If you miss an appointment, ask your doctor when to schedule your next dose. Do not stop treatment with Opdivo® unless you have discussed this with your doctor.

3. How does Opdivo® work?

Opdivo® is an immune checkpoint inhibitor that works with the T cells of your immune system to recognize and attack threats such as cancer cells.
Cancer cells can sometimes disguise themselves from T cells, allowing tumors to grow faster and spread quicker. Opdivo® essentially blocks cancer’s ability to disguise itself, which in turn activates T cells to attack, resulting in decreased tumor growth.

4. When to take Opdivo® infusion?

Opdivo® infusions are given either every 2 weeks or every 4 weeks when you’re receiving Opdivo® on its own. If you are receiving Opdivo® in combination with ipilimumab (Yervoy), your infusions will be every 3 weeks for your first four doses. After that, you will receive infusions of only Opdivo® every 2 or 4 weeks.

5. How long does it take to work?

It is not known exactly how long Opdivo® takes to work in your body. Your doctor will recommend that you come to their office every few weeks or months after you start taking Opdivo®. They will monitor your cancer at these appointments to see if the drug is working for you.